I don't know if this will find any of Izzy's children after all this time, but I just came across her obit.  I am saddened to see that she is gone.  I worked with Izzy at TMI back when I was Margy Augustine.  Knowing her and having the opportunity to be her friend was a true joy.  She had a keen sense of humor, was sharp as a tack, and loved each of her children fiercely.